Table 5 The existence of various miRNAs with pro- and anti-angiogenesis capacity
From: Tissue engineering strategies for the induction of angiogenesis using biomaterials
| miRNA | Function | Ref |
|---|---|---|
| miRNA-17-92 | Promotes angiogenesis by modulation of connective tissue growth factor, thrombospondin-1, and integrin α5 | [159] |
| miRNA-92a | Has a dual pro- and anti-angiogenic role | [160] |
| miRNA-21 | Increases VEGF level and promotes angiogenesis through a STAT3-dependent mechanism | [161] |
| miRNA-494 | Suppresses PTEN and activates Akt/eNOS pathway | [162] |
| miR-135b in exosomes from hypoxic multiple myeloma cells | Reduces the expression of FIH-1 and increased activity of HIF-1α | [163] |
| miR-125a | Promotes angiogenesis by inhibiting DLL-4 | [92] |